Advanced search×

Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.

Stanislaw R Burzynski, Tomasz J Janicki, Robert A Weaver, and Barbara Burzynski

Integr Cancer Ther 5(1):40-7 (2006) PMID 16484713

Brainstem glioma carries the worst prognosis of all malignancies of the brain. Most patients with brainstem glioma fail standard radiation therapy and chemotherapy and do not survive longer than 2 years. Treatment is even more challenging when an inoperable tumor is of high-grade pathology (HBSG). The objective of this report is to summarize the outcome of patients with HBSG treated with antineoplastons in 4 phase 2 trials. Patients: The following group of 18 patients was evaluable: 4 patients with glioblastomas and 14 patients with anaplastic HBSG. Fourteen patients had diffuse intrinsic tumors. Twelve patients suffered from recurrence, and 6 patients did not have radiation therapy or chemotherapy.

DOI: 10.1177/1534735405285380
Version: za2963e q8za4 q8zb7 q8zc1 q8zda q8ze4 q8zfc q8zg5
Buy PDF

Similar articles you may find interesting…

  1. Deep wound cultures and bone biopsy in diabetic foot osteomyelitis.
    M Malone, F L Bowling, and A J M Boulton

    Diabetes Metab Res Rev (2013) PMID 23653368

    Deep wound cultures correlate well with osseous cultures and provide a sensitive method in assessing and targeting likely pathogens that cause osseous infections. This will help aid the clinician in guiding antibiotic therapy in centers where bone biopsies may not be readily available. This article...
    Buy PDF
  2. Children's Oncology Group's 2013 blueprint for research: Bone tumors
    Richard Gorlick, Katherine Janeway, and Neyssa Marina

    Pediatr Blood Cancer 60(6):1009-1015 (2013) PMID 23255238

    In the US, approximately 650 children are diagnosed with osteosarcoma and Ewing sarcoma (ES) each year. Five-year survival ranges from 65% to 75% for localized disease and <30% for patients with metastases. Recent findings include interval-compressed five drug chemotherapy improves s...
    Buy PDF
  3. Value of cardiac 320-multidetector computed tomography and cardiac magnetic resonance imaging for assessment of myocardial perfusion defects...
    Abbas A Qayyum, Jørgen T Kühl, and Jens Kastrup

    Int J Cardiovasc Imaging (2013) PMID 23653247

    The challenge for therapies targeting perfusion abnormalities is to identify and evaluate the region of interest. The aim of this study was to compare rest and stress myocardial perfusion measured by cardiac multi-detector computed tomography (MDCT) and cardiac magnetic resonance (CM...
    Buy PDF